Mlf2 myeloid leukemia factor 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mlf2provided by RGD
Official Full Name: myeloid leukemia factor 2provided by RGD
Primary source: RGD:1306294
See related: EnsemblRapid:ENSRNOG00000016589 AllianceGenome:RGD:1306294
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in cytoplasm; glutamatergic synapse; and nucleus. Orthologous to human MLF2 (myeloid leukemia factor 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 604.2), Muscle (RPKM 485.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (159425542..159430584)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (157739651..157744325)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (157452578..157457254)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH128948 (e-PCR)
- UniSTS:212256

RH126138 (e-PCR)
- UniSTS:162850

RH136519 (e-PCR)
- UniSTS:210501

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
is_active_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: myeloid leukemia factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107889.1 → NP_001101359.1 myeloid leukemia factor 2

See identical proteins and their annotated locations for NP_001101359.1

Status: PROVISIONAL

Source sequence(s)

CH473964

UniProtKB/TrEMBL

A6ILN3, D3ZPN3

Conserved Domains (1) summary

pfam10248
Location:26 → 198

Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein