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    Vwa5b1 von Willebrand factor A domain containing 5B1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313653, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vwa5b1provided by RGD
    Official Full Name
    von Willebrand factor A domain containing 5B1provided by RGD
    Primary source
    RGD:1308559
    See related
    EnsemblRapid:ENSRNOG00000016553 AllianceGenome:RGD:1308559
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308559
    Summary
    Orthologous to human VWA5B1 (von Willebrand factor A domain containing 5B1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 28.2) and Brain (RPKM 4.4) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Vwa5b1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (156080599..156148155, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (150792959..150864849, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (157003505..157060553, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L12, pseudogene 13 Neighboring gene uncharacterized LOC120103014 Neighboring gene uncharacterized LOC108351047 Neighboring gene uncharacterized LOC108351048 Neighboring gene UBX domain protein 10 Neighboring gene phospholipase A2, group IIC

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    von Willebrand factor A domain-containing protein 5B1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107988.1 → NP_001101458.1  von Willebrand factor A domain-containing protein 5B1

      See identical proteins and their annotated locations for NP_001101458.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473968
      UniProtKB/TrEMBL
      A6ITI1, D3ZP60
      Related
      ENSRNOP00000022282.5, ENSRNOT00000022282.8
      Conserved Domains (2) summary
      cd01461
      Location:350 → 519
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      pfam13757
      Location:2 → 79
      VIT_2; Vault protein inter-alpha-trypsin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      156080599..156148155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287792.1 → XP_063143862.1  von Willebrand factor A domain-containing protein 5B1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADZ4

    2. XM_039110065.2 → XP_038965993.1  von Willebrand factor A domain-containing protein 5B1 isoform X1

      UniProtKB/TrEMBL
      A6ITI1, D3ZP60
      Conserved Domains (2) summary
      cd01461
      Location:350 → 519
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      pfam13757
      Location:2 → 79
      VIT_2; Vault protein inter-alpha-trypsin domain

    3. XM_006239199.5 → XP_006239261.1  von Willebrand factor A domain-containing protein 5B1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADZ4
      Related
      ENSRNOP00000092459.1, ENSRNOT00000094797.2
      Conserved Domains (3) summary
      cd01461
      Location:350 → 519
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      TIGR03788
      Location:18 → 561
      marine_srt_targ; marine proteobacterial sortase target protein
      pfam13757
      Location:2 → 79
      VIT_2; Vault protein inter-alpha-trypsin domain

    4. XM_063287790.1 → XP_063143860.1  von Willebrand factor A domain-containing protein 5B1 isoform X1

      UniProtKB/TrEMBL
      A6ITI1, D3ZP60

    5. XM_039110066.2 → XP_038965994.1  von Willebrand factor A domain-containing protein 5B1 isoform X3

      Conserved Domains (2) summary
      cd01461
      Location:350 → 519
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      pfam13757
      Location:2 → 79
      VIT_2; Vault protein inter-alpha-trypsin domain

    6. XM_039110067.2 → XP_038965995.1  von Willebrand factor A domain-containing protein 5B1 isoform X4

      Conserved Domains (2) summary
      cd01461
      Location:350 → 519
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      pfam13757
      Location:2 → 79
      VIT_2; Vault protein inter-alpha-trypsin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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