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    Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362652, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnajc16provided by RGD
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C16provided by RGD
    Primary source
    RGD:1359395
    See related
    EnsemblRapid:ENSRNOG00000012503 AllianceGenome:RGD:1359395
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ERdj8
    Summary
    Predicted to be involved in regulation of autophagosome size. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 100.6), Kidney (RPKM 89.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dnajc16 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (159355279..159389267, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (154073372..154106246, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (160325088..160352874, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and RUN domain containing M2 Neighboring gene DNA damage inducible 1 homolog 2 Neighboring gene agmatinase Neighboring gene caspase 9 Neighboring gene chymotrypsin like elastase 2A Neighboring gene chymotrypsin C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109011

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of autophagosome size ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of autophagosome size ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 16
    Names
    DnaJ (Hsp40) homolog, subfamily C, member 16
    ER-resident protein ERdj8
    endoplasmic reticulum DNA J domain-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014194.1 → NP_001014216.1  dnaJ homolog subfamily C member 16 precursor

      See identical proteins and their annotated locations for NP_001014216.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089875
      UniProtKB/Swiss-Prot
      Q5FVM7
      UniProtKB/TrEMBL
      A6ITW0
      Related
      ENSRNOP00000104110.1, ENSRNOT00000156428.1
      Conserved Domains (2) summary
      COG0484
      Location:29 → 134
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:133 → 242
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      159355279..159389267 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039110431.2 → XP_038966359.1  dnaJ homolog subfamily C member 16 isoform X1

      Conserved Domains (2) summary
      COG0484
      Location:29 → 134
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:133 → 242
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVM7.1 GenPept UniProtKB/Swiss-Prot:Q5FVM7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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