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    Tmem30b transmembrane protein 30B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314224, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem30bprovided by RGD
    Official Full Name
    transmembrane protein 30Bprovided by RGD
    Primary source
    RGD:1308732
    See related
    EnsemblRapid:ENSRNOG00000008046 AllianceGenome:RGD:1308732
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable aminophospholipid flippase activity. Predicted to be involved in aminophospholipid transport; phospholipid translocation; and positive regulation of protein exit from endoplasmic reticulum. Predicted to be part of phospholipid-translocating ATPase complex. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Tmem30b in Genome Data Viewer
    Location:
    6q24
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (97987471..97990546, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (92251626..92254702, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (96439607..96442682, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103552 Neighboring gene uncharacterized LOC102550345 Neighboring gene protein kinase C, eta Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene uncharacterized LOC120103553 Neighboring gene hypoxia inducible factor 1 subunit alpha

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables aminophospholipid flippase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in aminophospholipid translocation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in aminophospholipid transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phospholipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of protein exit from endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of phospholipid-translocating ATPase complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cell cycle control protein 50B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080380.3NP_001073849.1  cell cycle control protein 50B

      See identical proteins and their annotated locations for NP_001073849.1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HC62, D3Z9E9
      Related
      ENSRNOP00000010923.1, ENSRNOT00000010923.5
      Conserved Domains (1) summary
      pfam03381
      Location:60342
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      97987471..97990546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)