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    C2cd4c C2 calcium-dependent domain containing 4C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500798, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C2cd4cprovided by RGD
    Official Full Name
    C2 calcium-dependent domain containing 4Cprovided by RGD
    Primary source
    RGD:1561354
    See related
    EnsemblRapid:ENSRNOG00000073081 AllianceGenome:RGD:1561354
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam148c; RGD1561354
    Summary
    Predicted to be active in cytosol. Orthologous to human C2CD4C (C2 calcium dependent domain containing 4C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 27.3), Uterus (RPKM 13.7) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See C2cd4c in Genome Data Viewer
    Location:
    7q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (10742534..10746033)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (10090651..10095426)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (12973338..12978980)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene CIMAP1 family member D Neighboring gene SHC adaptor protein 2 Neighboring gene uncharacterized LOC134479817 Neighboring gene sperm microtubule associated protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. Omori H, et al. FEBS Lett, 2016 Aug. PMID 27349930, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    C2 calcium-dependent domain-containing protein 4C
    Names
    family with sequence similarity 148, member C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109285.1 → NP_001102755.1  C2 calcium-dependent domain-containing protein 4C

      See identical proteins and their annotated locations for NP_001102755.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474029
      UniProtKB/TrEMBL
      A6K8Z8, D3ZLU0
      Conserved Domains (2) summary
      smart00239
      Location:322 → 419
      C2; Protein kinase C conserved region 2 (CalB)
      PHA03307
      Location:53 → 303
      PHA03307; transcriptional regulator ICP4; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      10742534..10746033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006240985.5 → XP_006241047.1  C2 calcium-dependent domain-containing protein 4C isoform X1

      See identical proteins and their annotated locations for XP_006241047.1

      UniProtKB/TrEMBL
      A6K8Z8, D3ZLU0
      Related
      ENSRNOP00000109429.1, ENSRNOT00000142919.1
      Conserved Domains (2) summary
      smart00239
      Location:322 → 419
      C2; Protein kinase C conserved region 2 (CalB)
      PHA03307
      Location:53 → 303
      PHA03307; transcriptional regulator ICP4; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version

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