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    Tmem115 transmembrane protein 115 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363136, updated on 9-Dec-2024

    Summary

    Symbol
    Tmem115provided by RGD
    Full Name
    transmembrane protein 115provided by RGD
    Primary source
    RGD:1310540
    See related
    EnsemblRapid:ENSRNOG00000021899 AllianceGenome:RGD:1310540
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310540
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in Golgi cisterna membrane and nucleus. Predicted to be part of Golgi transport complex. Predicted to be active in Golgi apparatus. Orthologous to human TMEM115 (transmembrane protein 115). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 102.8), Lung (RPKM 92.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem115 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117086106..117090970)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108207463..108212327)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116289590..116294454)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 2 Neighboring gene uncharacterized LOC134480230 Neighboring gene uncharacterized LOC120094259 Neighboring gene cytochrome b561 family, member D2 Neighboring gene NPR2-like, GATOR1 complex subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi cisterna membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108779.2NP_001102249.1  transmembrane protein 115

      See identical proteins and their annotated locations for NP_001102249.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I2X2, D3ZE59
      Related
      ENSRNOP00000031879.4, ENSRNOT00000032263.7
      Conserved Domains (1) summary
      pfam08551
      Location:49151
      DUF1751; Eukaryotic integral membrane protein (DUF1751)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      117086106..117090970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)