Clul1 clusterin like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Clul1provided by RGD
Official Full Name: clusterin like 1provided by RGD
Primary source: RGD:1306852
See related: EnsemblRapid:ENSRNOG00000059237 AllianceGenome:RGD:1306852
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable misfolded protein binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space and nucleus. Orthologous to human CLUL1 (clusterin like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
Orthologs: human all
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Genomic context

Location:: 9q38

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (120791105..120816680, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (113344501..113370077, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (121944008..121972136, complement)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables misfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: clusterin-like protein 1

Names: clusterin-like 1 (retinal)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033071.1 → NP_001028243.1 clusterin-like protein 1 precursor

See identical proteins and their annotated locations for NP_001028243.1

Status: PROVISIONAL

Source sequence(s)

AY655707

UniProtKB/Swiss-Prot

Q3ZRW7

UniProtKB/TrEMBL

A0A0G2JZ07

Related

ENSRNOP00000070864.2, ENSRNOT00000089735.3

Conserved Domains (3) summary

smart00030
Location:29 → 226

CLb; CLUSTERIN Beta chain

smart00035
Location:247 → 458

CLa; CLUSTERIN alpha chain

pfam01093
Location:33 → 458

Clusterin; Clusterin