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    Gltpd2 glycolipid transfer protein domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497943, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gltpd2provided by RGD
    Official Full Name
    glycolipid transfer protein domain containing 2provided by RGD
    Primary source
    RGD:1560459
    See related
    EnsemblRapid:ENSRNOG00000070553 AllianceGenome:RGD:1560459
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560459
    Summary
    Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in membrane. Predicted to be active in cytosol. Orthologous to human GLTPD2 (glycolipid transfer protein domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 351.3) and Lung (RPKM 15.8) See more
    Orthologs
    NEW
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    Genomic context

    See Gltpd2 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55732199..55734974)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55233563..55236125)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57126127..57127783)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene transmembrane 4 L six family member 5 Neighboring gene vitelline membrane outer layer 1 homolog Neighboring gene chromosome 10 C17orf114 homolog Neighboring gene proteasome 20S subunit beta 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ceramide 1-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ceramide 1-phosphate transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in ceramide 1-phosphate transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ceramide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermembrane lipid transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glycolipid transfer protein domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115030.1NP_001108502.1  glycolipid transfer protein domain-containing protein 2

      See identical proteins and their annotated locations for NP_001108502.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158886
      UniProtKB/TrEMBL
      A0A8I5Y8A9, B0BNN1
      Related
      ENSRNOP00000077871.1, ENSRNOT00000095770.2
      Conserved Domains (1) summary
      pfam08718
      Location:140290
      GLTP; Glycolipid transfer protein (GLTP)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55732199..55734974
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086600.2XP_038942528.1  glycolipid transfer protein domain-containing protein 2 isoform X1