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    Fer1l4 fer-1-like family member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296307, updated on 9-Dec-2024

    Summary

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    Symbol
    Fer1l4provided by RGD
    Full Name
    fer-1-like family member 4provided by RGD
    Primary source
    RGD:1308250
    See related
    EnsemblRapid:ENSRNOG00000019467 AllianceGenome:RGD:1308250
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in plasma membrane organization. Predicted to be located in membrane. Orthologous to human FER1L4 (fer-1 like family member 4 (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 1.3), Thymus (RPKM 1.2) and 9 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See Fer1l4 in Genome Data Viewer
    Location:
    3q42
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (164996183..165031719, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (144536099..144571634, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (151564604..151600140, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene centrosomal protein 250 Neighboring gene similar to human chromosome 20 open reading frame 173 Neighboring gene ERGIC and golgi 3 Neighboring gene sperm associated antigen 4 Neighboring gene copine 1 Neighboring gene RNA binding motif protein 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in plasma membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fer-1-like protein 4
    Names
    fer-1-like 4
    fer-1-like protein 4-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106534.2 → NP_001100004.2  fer-1-like protein 4

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      D4ABP2
      Related
      ENSRNOP00000026451.5, ENSRNOT00000026451.7
      Conserved Domains (9) summary
      cd04011
      Location:224 → 334
      C2B_Ferlin; C2 domain second repeat in Ferlin
      cd04017
      Location:966 → 1100
      C2D_Ferlin; C2 domain fourth repeat in Ferlin
      cd04018
      Location:390 → 539
      C2C_Ferlin; C2 domain third repeat in Ferlin
      cd04037
      Location:1449 → 1572
      C2E_Ferlin; C2 domain fifth repeat in Ferlin
      cd08373
      Location:3 → 129
      C2A_Ferlin; C2 domain first repeat in Ferlin
      cd08374
      Location:1692 → 1825
      C2F_Ferlin; C2 domain sixth repeat in Ferlin
      pfam08150
      Location:861 → 930
      FerB; FerB (NUC096) domain
      pfam08151
      Location:332 → 382
      FerI; FerI (NUC094) domain
      pfam16165
      Location:1834 → 1985
      Ferlin_C; Ferlin C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      164996183..165031719 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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