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    Slc16a4 solute carrier family 16, member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295356, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc16a4provided by RGD
    Official Full Name
    solute carrier family 16, member 4provided by RGD
    Primary source
    RGD:1359655
    See related
    EnsemblRapid:ENSRNOG00000018131 AllianceGenome:RGD:1359655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in carboxylic acid transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human SLC16A4 (solute carrier family 16 member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 257.7), Liver (RPKM 85.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc16a4 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (197593738..197621569)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (194911075..194933162)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (210045122..210161017)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485948 Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Neighboring gene RNA binding motif protein 15 Neighboring gene ribosomal protein S13, pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables monocarboxylic acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carboxylic acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monocarboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    monocarboxylate transporter 5
    Names
    solute carrier family 16 (monocarboxylic acid transporters), member 4
    solute carrier family 16, member 4 (monocarboxylic acid transporter 5)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013913.1 → NP_001013935.1  monocarboxylate transporter 5

      See identical proteins and their annotated locations for NP_001013935.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085920
      UniProtKB/TrEMBL
      D3ZFJ5, Q5U2P9
      Related
      ENSRNOP00000092859.2, ENSRNOT00000100305.2
      Conserved Domains (1) summary
      cd17421
      Location:20 → 486
      MFS_MCT5; Monocarboxylate transporter 5 of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      197593738..197621569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102076.2 → XP_038958004.1  monocarboxylate transporter 5 isoform X1

      UniProtKB/TrEMBL
      D3ZFJ5, Q5U2P9
      Conserved Domains (1) summary
      cd17421
      Location:20 → 486
      MFS_MCT5; Monocarboxylate transporter 5 of the Major Facilitator Superfamily of transporters

    2. XM_008761389.3 → XP_008759611.1  monocarboxylate transporter 5 isoform X3

      See identical proteins and their annotated locations for XP_008759611.1

      UniProtKB/TrEMBL
      A0A8I6AID2, A6HUT7
      Conserved Domains (2) summary
      cd06174
      Location:24 → 309
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00892
      Location:6 → 306
      2A0113; monocarboxylate transporter 1

    3. XM_063281656.1 → XP_063137726.1  monocarboxylate transporter 5 isoform X2

      Related
      ENSRNOP00000024455.6, ENSRNOT00000024455.8
    Nucleotide Protein Strain
    Heading Accession and Version

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