Actl9b actin-like 9b [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Actl9bprovided by RGD
Official Full Name: actin-like 9bprovided by RGD
Primary source: RGD:1359476
See related: EnsemblRapid:ENSRNOG00000026033 AllianceGenome:RGD:1359476
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Actl9
Summary: Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in several processes, including acrosome assembly; axonogenesis; and fertilization. Predicted to be located in acrosomal vesicle; perinuclear theca; and sperm head. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in several cellular components, including actin filament; axon; and synapse. Human ortholog(s) of this gene implicated in spermatogenic failure 53. Orthologous to human ACTL9 (actin like 9). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 1q12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (72745456..72746793, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (63830481..63831818, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (4085836..4087173)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in acrosome assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in fertilization	ISS Inferred from Sequence or Structural Similarity more info
involved_in postsynaptic actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in single fertilization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in acrosomal vesicle	ISS Inferred from Sequence or Structural Similarity more info
is_active_in actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in perinuclear theca	ISS Inferred from Sequence or Structural Similarity more info
located_in sperm head	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: actin-like protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013893.1 → NP_001013915.1 actin-like protein 9

See identical proteins and their annotated locations for NP_001013915.1

Status: PROVISIONAL

Source sequence(s)

BC079230

UniProtKB/Swiss-Prot

Q6AY16

Related

ENSRNOP00000037574.2, ENSRNOT00000031286.6

Conserved Domains (2) summary

pfam00022
Location:47 → 411

Actin; Actin

cl17037
Location:45 → 410

NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily