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    Csn1s1 casein alpha s1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24284, updated on 9-Dec-2024

    Summary

    Official Symbol
    Csn1s1provided by RGD
    Official Full Name
    casein alpha s1provided by RGD
    Primary source
    RGD:2430
    See related
    AllianceGenome:RGD:2430
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Casa; Csn1; Csna
    Summary
    Predicted to be involved in several processes, including response to 11-deoxycorticosterone; response to dehydroepiandrosterone; and response to progesterone. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CSN1S1 (casein alpha s1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 48.0) See more
    Orthologs
    NEW
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    Genomic context

    See Csn1s1 in Genome Data Viewer
    Location:
    14p21
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (20622858..20638849, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (20343620..20359614, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (21993450..22009308, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene statherin Neighboring gene casein beta Neighboring gene ribosomal protein L30, pseudogene 7 Neighboring gene uncharacterized LOC120096585

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in response to 11-deoxycorticosterone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to dehydroepiandrosterone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to estradiol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to progesterone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    alpha-S1-casein
    Names
    Casein, alpha
    alpha-casein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138874.2NP_620229.2  alpha-S1-casein precursor

      See identical proteins and their annotated locations for NP_620229.2

      Status: PROVISIONAL

      Source sequence(s)
      J00710
      UniProtKB/Swiss-Prot
      P02661
      UniProtKB/TrEMBL
      A6KU22
      Conserved Domains (1) summary
      pfam00363
      Location:195263
      Casein; Casein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      20622858..20638849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063272857.1XP_063128927.1  alpha-S1-casein isoform X1