U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Akap17a A-kinase anchoring protein 17A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288526, updated on 9-Dec-2024

    Summary

    Official Symbol
    Akap17aprovided by RGD
    Official Full Name
    A-kinase anchoring protein 17Aprovided by RGD
    Primary source
    RGD:1564640
    See related
    EnsemblRapid:ENSRNOG00000028211 AllianceGenome:RGD:1564640
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein kinase A binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Predicted to be active in cytosol and nuclear speck. Orthologous to human AKAP17A (A-kinase anchoring protein 17A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 73.3), Spleen (RPKM 56.6) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Akap17a in Genome Data Viewer
    Location:
    12q11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (21424202..21428308, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (16310427..16315166, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (18527116..18531780, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase X-linked Neighboring gene acetylserotonin O-methyltransferase Neighboring gene acetylserotonin O-methyltransferase-like Neighboring gene interleukin 3 receptor subunit alpha

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleic acid binding  
    enables protein kinase A binding  
    enables protein kinase A binding  
    Process Evidence Code Pubs
    involved_in regulation of RNA splicing  
    involved_in regulation of RNA splicing  
    Component Evidence Code Pubs
    is_active_in cytosol  
    located_in cytosol  
    is_active_in nuclear speck  
    located_in nuclear speck  
    located_in nucleus  

    General protein information

    Preferred Names
    A-kinase anchor protein 17A
    Names
    A kinase (PRKA) anchor protein 17A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127246.2NP_001120718.2  A-kinase anchor protein 17A

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      B2RYB9, F1MAF2
      Related
      ENSRNOP00000032594.4, ENSRNOT00000037829.6
      Conserved Domains (2) summary
      pfam15709
      Location:282445
      DUF4670; Domain of unknown function (DUF4670)
      cl17169
      Location:147278
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      21424202..21428308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248999.4XP_006249061.1  A-kinase anchor protein 17A isoform X1

      See identical proteins and their annotated locations for XP_006249061.1

      UniProtKB/TrEMBL
      B2RYB9, F1MAF2
      Conserved Domains (2) summary
      pfam15709
      Location:282445
      DUF4670; Domain of unknown function (DUF4670)
      cl17169
      Location:147278
      RRM_SF; RNA recognition motif (RRM) superfamily
    2. XM_006249000.4XP_006249062.1  A-kinase anchor protein 17A isoform X1

      See identical proteins and their annotated locations for XP_006249062.1

      UniProtKB/TrEMBL
      B2RYB9, F1MAF2
      Conserved Domains (2) summary
      pfam15709
      Location:282445
      DUF4670; Domain of unknown function (DUF4670)
      cl17169
      Location:147278
      RRM_SF; RNA recognition motif (RRM) superfamily
    3. XM_006248998.4XP_006249060.1  A-kinase anchor protein 17A isoform X1

      See identical proteins and their annotated locations for XP_006249060.1

      UniProtKB/TrEMBL
      B2RYB9, F1MAF2
      Conserved Domains (2) summary
      pfam15709
      Location:282445
      DUF4670; Domain of unknown function (DUF4670)
      cl17169
      Location:147278
      RRM_SF; RNA recognition motif (RRM) superfamily
    External link. Please review our privacy policy.