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    Acoxl acyl-CoA oxidase-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296138, updated on 9-Dec-2024

    Summary

    Official Symbol
    Acoxlprovided by RGD
    Official Full Name
    acyl-CoA oxidase-likeprovided by RGD
    Primary source
    RGD:1306814
    See related
    EnsemblRapid:ENSRNOG00000016179 AllianceGenome:RGD:1306814
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be active in peroxisome. Orthologous to human ACOXL (acyl-CoA oxidase like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 108.7) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Acoxl in Genome Data Viewer
    Location:
    3q36
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (135514340..135820291)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (115061069..115367032)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (120414311..120724809)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene mitoregulin Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase Neighboring gene Bcl2-like 11 Neighboring gene uncharacterized LOC102555576 Neighboring gene small ribosomal subunit protein uS17-like Neighboring gene small nuclear ribonucleoprotein polypeptide F, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyl-CoA oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fatty acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation using acyl-CoA oxidase IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    acyl-coenzyme A oxidase-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106508.2NP_001099978.1  acyl-coenzyme A oxidase-like protein isoform 2

      See identical proteins and their annotated locations for NP_001099978.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A0G2K3T0, A6HQ29, D4A257
      Related
      ENSRNOP00000103685.1, ENSRNOT00000121375.1
      Conserved Domains (2) summary
      PLN02636
      Location:63601
      PLN02636; acyl-coenzyme A oxidase
      cl09933
      Location:63601
      ACAD; Acyl-CoA dehydrogenase
    2. NM_001415677.1NP_001402606.1  acyl-coenzyme A oxidase-like protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A0G2K3T0, A0A8I5ZRR5
      Related
      ENSRNOP00000108685.1, ENSRNOT00000167199.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      135514340..135820291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)