Noc4l nucleolar complex associated 4 homolog [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Noc4lprovided by RGD
Official Full Name: nucleolar complex associated 4 homologprovided by RGD
Primary source: RGD:1310661
See related: EnsemblRapid:ENSRNOG00000037478 AllianceGenome:RGD:1310661
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1310661
Summary: Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOC4L (nucleolar complex associated 4 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 50.2), Thymus (RPKM 46.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q16

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (51675852..51680392)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (46016077..46020615)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (52072190..52076728)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Noc4p-Nop14p complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nucleolar complex protein 4 homolog

Names: NOC4 protein homolog; NOC4-like protein; nucleolar complex-associated protein 4-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014129.1 → NP_001014151.1 nucleolar complex protein 4 homolog

See identical proteins and their annotated locations for NP_001014151.1

Status: PROVISIONAL

Source sequence(s)

BC088275

UniProtKB/Swiss-Prot

Q5I0I8

UniProtKB/TrEMBL

A0A8L2QRA3, A6J298

Related

ENSRNOP00000053566.3, ENSRNOT00000056725.4

Conserved Domains (2) summary

COG5117
Location:96 → 453

NOC3; Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion]

pfam03914
Location:305 → 453

CBF; CBF/Mak21 family