Iah1 isoamyl acetate hydrolyzing esterase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Iah1provided by RGD
Official Full Name: isoamyl acetate hydrolyzing esterase 1provided by RGD
Primary source: RGD:727866
See related: EnsemblRapid:ENSRNOG00000060853 AllianceGenome:RGD:727866
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Harpb64
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in lipid catabolic process. Orthologous to human IAH1 (isoamyl acetate hydrolyzing esterase 1 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 1565.3), Liver (RPKM 587.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q16

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (46594177..46601394)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (40865530..40872747)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (43393113..43400330)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH141932 (e-PCR)
- UniSTS:223923

RH128637 (e-PCR)
- UniSTS:211945

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables hydrolase activity, acting on ester bonds	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in lipid catabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: isoamyl acetate-hydrolyzing esterase 1 homolog

Names: hypertrophic agonist-responsive protein B64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100540.1 → NP_001094010.1 isoamyl acetate-hydrolyzing esterase 1 homolog

See identical proteins and their annotated locations for NP_001094010.1

Status: PROVISIONAL

Source sequence(s)

BC168771

UniProtKB/Swiss-Prot

Q711G3

UniProtKB/TrEMBL

B5DER3

Related

ENSRNOP00000068696.1, ENSRNOT00000087180.3

Conserved Domains (1) summary

cd01838
Location:17 → 217

Isoamyl_acetate_hydrolase_like; Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash. The SGNH-family of hydrolases is a diverse family of ...