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    Zfp605 zinc finger protein 605 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100365779, updated on 27-Dec-2024

    Summary

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    Symbol
    Zfp605provided by RGD
    Full Name
    zinc finger protein 605provided by RGD
    Primary source
    RGD:2318406
    See related
    EnsemblRapid:ENSRNOG00000037428 AllianceGenome:RGD:2318406
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF605 (zinc finger protein 605). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 66.1), Adrenal (RPKM 30.5) and 9 other tissues See more
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    Genomic context

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    See Zfp605 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (52202487..52234782, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (46542771..46575074, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (52606554..52670918, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene golgin A3 Neighboring gene uncharacterized LOC134481217 Neighboring gene checkpoint with forkhead and ring finger domains Neighboring gene RIKEN cDNA B230307C23 gene like Neighboring gene GTP binding protein 6 (putative) Neighboring gene phosphatidylinositol-specific phospholipase C, X domain containing 1 Neighboring gene zinc finger protein 950 like 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 350; zinc finger protein 605
    Names
    mCG142312-like
    zinc finger protein 350-like
    zinc finger protein 850-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432381.1 → NP_001419310.1  zinc finger protein 605 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      F1M278

    2. NM_001432382.1 → NP_001419311.1  zinc finger protein 605 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      F1M278

    3. NM_001432383.1 → NP_001419312.1  zinc finger protein 605 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      F1M278

    4. NM_001432384.1 → NP_001419313.1  zinc finger protein 605 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      F1M278

    5. NM_001432385.1 → NP_001419314.1  zinc finger protein 605 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      F1M278

    6. NM_001432386.1 → NP_001419315.1  zinc finger protein 605 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    7. NM_001432387.1 → NP_001419316.1  zinc finger protein 605 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    8. NM_001432388.1 → NP_001419317.1  zinc finger protein 605 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    9. NM_001432389.1 → NP_001419318.1  zinc finger protein 605 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    10. NM_001432390.1 → NP_001419319.1  zinc finger protein 605 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    11. NM_001432391.1 → NP_001419320.1  zinc finger protein 605 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    12. NM_001432392.1 → NP_001419321.1  zinc finger protein 605 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    13. NM_001432393.1 → NP_001419322.1  zinc finger protein 605 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    14. NM_001432394.1 → NP_001419323.1  zinc finger protein 605 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    15. NM_001432395.1 → NP_001419324.1  zinc finger protein 605 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    16. NM_001432396.1 → NP_001419325.1  zinc finger protein 605 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    17. NM_001432397.1 → NP_001419326.1  zinc finger protein 605 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    18. NM_001432398.1 → NP_001419327.1  zinc finger protein 605 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J2D2

    19. NM_001432399.1 → NP_001419328.1  zinc finger protein 605 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J2D2

    20. NM_001432400.1 → NP_001419329.1  zinc finger protein 605 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J2D2

    RNA

    1. NR_197282.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    2. NR_197283.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      52202487..52234782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271811.1 → XP_063127881.1  zinc finger protein 605 isoform X3

    2. XM_017598571.3 → XP_017454060.1  zinc finger protein 605 isoform X1

      Conserved Domains (5) summary
      smart00349
      Location:8 → 63
      KRAB; krueppel associated box
      COG5048
      Location:362 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:535 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 46
      KRAB; KRAB box
      pfam13465
      Location:632 → 656
      zf-H2C2_2; Zinc-finger double domain

    3. XM_017598574.3 → XP_017454063.1  zinc finger protein 605 isoform X2

      UniProtKB/TrEMBL
      F1M278
      Conserved Domains (3) summary
      COG5048
      Location:296 → 684
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:469 → 489
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:566 → 590
      zf-H2C2_2; Zinc-finger double domain

    4. XM_017598575.3 → XP_017454064.1  zinc finger protein 605 isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:264 → 652
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:437 → 457
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_017598568.3 → XP_017454057.1  zinc finger protein 605 isoform X1

      Related
      ENSRNOP00000044439.5, ENSRNOT00000041981.6
      Conserved Domains (5) summary
      smart00349
      Location:8 → 63
      KRAB; krueppel associated box
      COG5048
      Location:362 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:535 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 46
      KRAB; KRAB box
      pfam13465
      Location:632 → 656
      zf-H2C2_2; Zinc-finger double domain

    6. XM_063271807.1 → XP_063127877.1  zinc finger protein 605 isoform X3

    7. XM_063271812.1 → XP_063127882.1  zinc finger protein 605 isoform X3

    8. XM_017598572.3 → XP_017454061.1  zinc finger protein 605 isoform X1

      Conserved Domains (5) summary
      smart00349
      Location:8 → 63
      KRAB; krueppel associated box
      COG5048
      Location:362 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:535 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 46
      KRAB; KRAB box
      pfam13465
      Location:632 → 656
      zf-H2C2_2; Zinc-finger double domain

    9. XM_063271806.1 → XP_063127876.1  zinc finger protein 605 isoform X2

    10. XM_063271810.1 → XP_063127880.1  zinc finger protein 605 isoform X3

    11. XM_017598569.3 → XP_017454058.1  zinc finger protein 605 isoform X1

      Related
      ENSRNOP00000103928.1, ENSRNOT00000161815.1
      Conserved Domains (5) summary
      smart00349
      Location:8 → 63
      KRAB; krueppel associated box
      COG5048
      Location:362 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:535 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 46
      KRAB; KRAB box
      pfam13465
      Location:632 → 656
      zf-H2C2_2; Zinc-finger double domain

    12. XM_063271808.1 → XP_063127878.1  zinc finger protein 605 isoform X3

    13. XM_017598570.3 → XP_017454059.1  zinc finger protein 605 isoform X1

      Conserved Domains (5) summary
      smart00349
      Location:8 → 63
      KRAB; krueppel associated box
      COG5048
      Location:362 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:535 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 46
      KRAB; KRAB box
      pfam13465
      Location:632 → 656
      zf-H2C2_2; Zinc-finger double domain

    14. XM_063271809.1 → XP_063127879.1  zinc finger protein 605 isoform X3

    15. XM_063271813.1 → XP_063127883.1  zinc finger protein 350 isoform X4

    RNA

    1. XR_010056633.1 RNA Sequence

    2. XR_005492102.2 RNA Sequence

    3. XR_010056630.1 RNA Sequence

    4. XR_010056631.1 RNA Sequence

    5. XR_010056629.1 RNA Sequence

    6. XR_010056634.1 RNA Sequence

    7. XR_010056632.1 RNA Sequence

    8. XR_010056628.1 RNA Sequence

    9. XR_010056635.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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