Taf13 TATA-box binding protein associated factor 13 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Taf13provided by RGD
Official Full Name: TATA-box binding protein associated factor 13provided by RGD
Primary source: RGD:1305398
See related: EnsemblRapid:ENSRNOG00000020315 AllianceGenome:RGD:1305398
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA binding activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; mRNA transcription by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 60. Orthologous to human TAF13 (TATA-box binding protein associated factor 13). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 136.6), Kidney (RPKM 98.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (198893332..198903994)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (196205219..196215882)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (211359623..211370285)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

UniSTS:234805 (e-PCR)
- UniSTS:234805

D2Rat236 (e-PCR), detects polymorphism
- UniSTS:227385

RH140088 (e-PCR)
- UniSTS:222169

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables TBP-class protein binding	ISO Inferred from Sequence Orthology more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in mRNA transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription initiation by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIID complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: transcription initiation factor TFIID subunit 13

Names: TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001303616.1 → NP_001290545.1 transcription initiation factor TFIID subunit 13

See identical proteins and their annotated locations for NP_001290545.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript. It encodes the protein.

Source sequence(s)

AW144407, FM054549, FM135814, JAXUCZ010000002

UniProtKB/TrEMBL

A0A9K3Y8H1, B2RYQ7, F7F1P7

Related

ENSRNOP00000111092.1, ENSRNOT00000171011.1

Conserved Domains (1) summary

cd07978
Location:29 → 118

TAF13; The TATA Binding Protein (TBP) Associated Factor 13 (TAF13) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

RNA

NR_130639.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an internal exon compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.

Source sequence(s)

AW144407, CB557548, JAXUCZ010000002

Related

ENSRNOT00000027530.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

198893332..198903994

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001107716.1: Suppressed sequence

Description

NM_001107716.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.