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    Ino80e INO80 complex subunit E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293494, updated on 4-Jan-2025

    Summary

    Official Symbol
    Ino80eprovided by RGD
    Official Full Name
    INO80 complex subunit Eprovided by RGD
    Primary source
    RGD:1359572
    See related
    EnsemblRapid:ENSRNOG00000019960 AllianceGenome:RGD:1359572
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc95
    Summary
    Predicted to be involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Ino80 complex. Orthologous to human INO80E (INO80 complex subunit E). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Brain (RPKM 97.2), Kidney (RPKM 90.9) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ino80e in Genome Data Viewer
    Location:
    1q36
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (190891315..190902902, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181461406..181472059, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (198287489..198298076, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene TLC domain containing 3B Neighboring gene uncharacterized LOC134483857 Neighboring gene similar to human chromosome 16 open reading frame 92 Neighboring gene double C2 domain alpha Neighboring gene HIRA interacting protein 3 Neighboring gene TAO kinase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA recombination  
    involved_in DNA repair  
    involved_in biological_process  
    involved_in chromatin remodeling  
    involved_in chromatin remodeling  
    involved_in positive regulation of DNA-templated transcription  
    involved_in regulation of DNA replication  
    involved_in regulation of DNA strand elongation  
    involved_in regulation of cell cycle  
    involved_in regulation of chromosome organization  
    Component Evidence Code Pubs
    part_of Ino80 complex  
    part_of Ino80 complex  
    part_of Ino80 complex  
    located_in nucleolus  
    located_in nucleolus  
    located_in nucleoplasm  
    located_in nucleoplasm  

    General protein information

    Preferred Names
    INO80 complex subunit E
    Names
    coiled-coil domain containing 95
    coiled-coil domain-containing protein 95

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013900.1NP_001013922.1  INO80 complex subunit E

      See identical proteins and their annotated locations for NP_001013922.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079045
      UniProtKB/Swiss-Prot
      Q6AYH2
      UniProtKB/TrEMBL
      A0A8I6G9J0, A6I9G3
      Related
      ENSRNOP00000027034.5, ENSRNOT00000027033.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      190891315..190902902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286191.1XP_063142261.1  INO80 complex subunit E isoform X9

    2. XM_063286198.1XP_063142268.1  INO80 complex subunit E isoform X11

      UniProtKB/TrEMBL
      A6I9G9
    3. XM_063286185.1XP_063142255.1  INO80 complex subunit E isoform X8

    4. XM_063286151.1XP_063142221.1  INO80 complex subunit E isoform X1

      UniProtKB/Swiss-Prot
      Q6AYH2
      UniProtKB/TrEMBL
      A0A8I6G9J0, A6I9G3
    5. XM_063286152.1XP_063142222.1  INO80 complex subunit E isoform X1

      UniProtKB/Swiss-Prot
      Q6AYH2
      UniProtKB/TrEMBL
      A0A8I6G9J0, A6I9G3
    6. XM_063286175.1XP_063142245.1  INO80 complex subunit E isoform X6

      UniProtKB/TrEMBL
      A0A8I6G9J0
    7. XM_063286168.1XP_063142238.1  INO80 complex subunit E isoform X4

      UniProtKB/TrEMBL
      A0A8I6G9J0
    8. XM_006230243.4XP_006230305.1  INO80 complex subunit E isoform X2

      UniProtKB/TrEMBL
      A0A8I6G9J0
      Conserved Domains (1) summary
      pfam08537
      Location:1297
      NBP1; Fungal Nap binding protein NBP1
    9. XM_006230245.4XP_006230307.1  INO80 complex subunit E isoform X5

      UniProtKB/TrEMBL
      A0A8I6G9J0, A0A8L2UKE2
      Related
      ENSRNOP00000083835.2, ENSRNOT00000107197.2
      Conserved Domains (1) summary
      pfam08537
      Location:1265
      NBP1; Fungal Nap binding protein NBP1
    10. XM_006230244.4XP_006230306.1  INO80 complex subunit E isoform X3

      UniProtKB/TrEMBL
      A0A8I6G9J0
    11. XM_039107436.1XP_038963364.1  INO80 complex subunit E isoform X12

      UniProtKB/TrEMBL
      A0A8I6A0H5, A6I9G5, A6I9G8
    12. XM_039107432.1XP_038963360.1  INO80 complex subunit E isoform X12

      UniProtKB/TrEMBL
      A0A8I6A0H5, A6I9G5, A6I9G8
    13. XM_039107430.2XP_038963358.1  INO80 complex subunit E isoform X10

    14. XM_017588993.3XP_017444482.1  INO80 complex subunit E isoform X7

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