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    Slc31a2 solute carrier family 31 member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298091, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc31a2provided by RGD
    Official Full Name
    solute carrier family 31 member 2provided by RGD
    Primary source
    RGD:1307963
    See related
    EnsemblRapid:ENSRNOG00000013631 AllianceGenome:RGD:1307963
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion import. Predicted to act upstream of or within intracellular copper ion homeostasis and regulation of copper ion transmembrane transport. Predicted to be located in endosome; lysosomal membrane; and plasma membrane. Orthologous to human SLC31A2 (solute carrier family 31 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 165.6), Lung (RPKM 67.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc31a2 in Genome Data Viewer
    Location:
    5q24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (80753589..80764126)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (75738008..75748542)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (78120606..78131111)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350981 Neighboring gene uncharacterized LOC134478995 Neighboring gene FKBP prolyl isomerase family member 15 Neighboring gene solute carrier family 31 member 1 Neighboring gene cell division cycle 26

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Clone Names

    • MGC124776

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables copper ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables copper ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein SLC31A2
    Names
    probable low affinity copper uptake protein 2
    solute carrier family 31 (copper transporter), member 2
    solute carrier family 31 (copper transporters), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033693.2NP_001028865.2  protein SLC31A2

      See identical proteins and their annotated locations for NP_001028865.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I6A3L3, A6J7T6, D4AAE7
      Related
      ENSRNOP00000019379.5, ENSRNOT00000019379.9
      Conserved Domains (1) summary
      pfam04145
      Location:3135
      Ctr; Ctr copper transporter family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      80753589..80764126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109465.2XP_038965393.1  protein SLC31A2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A3L3
      Conserved Domains (1) summary
      pfam04145
      Location:15110
      Ctr; Ctr copper transporter family