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    Rpl15 ribosomal protein L15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 245981, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpl15provided by RGD
    Official Full Name
    ribosomal protein L15provided by RGD
    Primary source
    RGD:621181
    See related
    EnsemblRapid:ENSRNOG00000008140 AllianceGenome:RGD:621181
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rpl10
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in response to ethanol. Located in A band. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 12. Orthologous to human RPL15 (ribosomal protein L15). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 1290.7), Spleen (RPKM 1283.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpl15 in Genome Data Viewer
    Location:
    15p16
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (9934663..9937946)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (7503883..7507166)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (8188717..8192153)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2E 1 Neighboring gene uncharacterized protein DDB_G0290685-like Neighboring gene NFKB inhibitor interacting Ras-like 1 Neighboring gene nuclear receptor subfamily 1, group D, member 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase like 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to ethanol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in A band IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein eL15
    Names
    60S ribosomal protein L15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139114.3NP_620814.1  large ribosomal subunit protein eL15

      See identical proteins and their annotated locations for NP_620814.1

      Status: VALIDATED

      Source sequence(s)
      AA687059, BC078724
      UniProtKB/Swiss-Prot
      P61314
      UniProtKB/TrEMBL
      A0A8I6A471, A6K036
      Related
      ENSRNOP00000010759.3, ENSRNOT00000010759.8
      Conserved Domains (1) summary
      pfam00827
      Location:2191
      Ribosomal_L15e; Ribosomal L15

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      9934663..9937946
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)