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    Chst9 carbohydrate sulfotransferase 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291770, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Chst9provided by RGD
    Official Full Name
    carbohydrate sulfotransferase 9provided by RGD
    Primary source
    RGD:1307302
    See related
    EnsemblRapid:ENSRNOG00000015867 AllianceGenome:RGD:1307302
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in proteoglycan biosynthetic process and sulfur compound metabolic process. Predicted to be located in Golgi membrane. Orthologous to human CHST9 (carbohydrate sulfotransferase 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 35.8), Liver (RPKM 15.5) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Chst9 in Genome Data Viewer
    Location:
    18p13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (6850874..7125222, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (6576391..6851078, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (6833408..7115815, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene rRNA 2'-O-methyltransferase fibrillarin-like Neighboring gene uncharacterized LOC134482912 Neighboring gene uncharacterized LOC134482913 Neighboring gene uncharacterized LOC108348751 Neighboring gene prohibitin 1, pseudogene 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and expression of an N-acetylgalactosamine-4-O-sulfotransferase that transfers sulfate to terminal and non-terminal beta 1,4-linked N-acetylgalactosamine. Kang HG, et al. J Biol Chem, 2001 Apr 6. PMID 11139592
    2. Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl. Okuda T, et al. J Biochem, 2003 Jul. PMID 12944377
    3. Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1-->4GlcNAc beta 1-->R in both N- and O-glycans. Hiraoka N, et al. Glycobiology, 2001 Jun. PMID 11445554
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dermatan 4-sulfotransferase ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carbohydrate sulfotransferase 9
    Names
    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
    NP_001163941.1
    XP_008770158.2
    XP_017456411.1
    XP_063133334.1
    XP_063133335.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170470.1 → NP_001163941.1  carbohydrate sulfotransferase 9

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      F1M862
      Related
      ENSRNOP00000021253.6, ENSRNOT00000021253.8
      Conserved Domains (1) summary
      pfam03567
      Location:180 → 409
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      6850874..7125222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600922.3 → XP_017456411.1  carbohydrate sulfotransferase 9 isoform X1

      UniProtKB/TrEMBL
      F1M862
      Conserved Domains (1) summary
      pfam03567
      Location:180 → 409
      Sulfotransfer_2; Sulfotransferase family

    2. XM_063277265.1 → XP_063133335.1  carbohydrate sulfotransferase 9 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZVI1

    3. XM_063277264.1 → XP_063133334.1  carbohydrate sulfotransferase 9 isoform X1

      UniProtKB/TrEMBL
      F1M862

    4. XM_008771936.4 → XP_008770158.2  carbohydrate sulfotransferase 9 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZVI1
      Related
      ENSRNOP00000082918.1, ENSRNOT00000098563.2
    Nucleotide Protein Strain
    Heading Accession and Version

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