U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Hsbp1l1 heat shock factor binding protein 1-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100192205, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hsbp1l1provided by RGD
    Official Full Name
    heat shock factor binding protein 1-like 1provided by RGD
    Primary source
    RGD:2301798
    See related
    EnsemblRapid:ENSRNOG00000059055 AllianceGenome:RGD:2301798
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in cellular heat acclimation. Predicted to be active in cytosol and nucleus. Orthologous to human HSBP1L1 (heat shock factor binding protein 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 13.2), Lung (RPKM 12.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Hsbp1l1 in Genome Data Viewer
    Location:
    18q12.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (75957266..75963024, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (73682286..73690061, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (76748067..76754642, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene ribosome binding factor A Neighboring gene thioredoxin-like 4A Neighboring gene N(alpha)-acetyltransferase 12, NatA catalytic subunit Neighboring gene solute carrier family 66 member 2 Neighboring gene potassium voltage-gated channel modifier subfamily G member 2 Neighboring gene uncharacterized LOC120098179

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular heat acclimation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    heat shock factor-binding protein 1-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136183.1NP_001129655.1  heat shock factor-binding protein 1-like protein 1

      See identical proteins and their annotated locations for NP_001129655.1

      Status: VALIDATED

      Source sequence(s)
      CB787859, CR474979
      UniProtKB/Swiss-Prot
      D4A9E1
      Related
      ENSRNOP00000071103.1, ENSRNOT00000078797.3
      Conserved Domains (1) summary
      pfam06825
      Location:1462
      HSBP1; Heat shock factor binding protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      75957266..75963024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)