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    Chmp1b2 charged multivesicular body protein 1B2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363487, updated on 9-Dec-2024

    Summary

    Official Symbol
    Chmp1b2provided by RGD
    Official Full Name
    charged multivesicular body protein 1B2provided by RGD
    Primary source
    RGD:1566265
    See related
    EnsemblRapid:ENSRNOG00000002323 AllianceGenome:RGD:1566265
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566265
    Summary
    Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Orthologous to human CHMP1B (charged multivesicular body protein 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 73.3), Thymus (RPKM 68.9) and 9 other tissues See more
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    Genomic context

    See Chmp1b2 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (76933194..76974018, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (72860409..72901232, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (78870964..78911601, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene putative transmembrane protein 217B Neighboring gene forkhead box N2, pseudogene 1 Neighboring gene T-box transcription factor 22 Neighboring gene terminal nucleotidyltransferase 5D Neighboring gene WASP family member 1 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in endosome transport via multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in late endosome to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of ESCRT III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in multivesicular body IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    charged multivesicular body protein 1B2
    Names
    Charged multivesicular body protein 1b-2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134589.1NP_001128061.1  charged multivesicular body protein 1B2

      See identical proteins and their annotated locations for NP_001128061.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473969
      UniProtKB/TrEMBL
      A0A8I6AP66, A6IV71, G3V6A6
      Related
      ENSRNOP00000003188.5, ENSRNOT00000003188.7
      Conserved Domains (1) summary
      cl21588
      Location:49165
      Snf7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      76933194..76974018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)