Slc35d2 solute carrier family 35 member D2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc35d2provided by RGD
Official Full Name: solute carrier family 35 member D2provided by RGD
Primary source: RGD:1309518
See related: EnsemblRapid:ENSRNOG00000027229 AllianceGenome:RGD:1309518
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable antiporter activity and pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in nucleotide-sugar transmembrane transport. Predicted to act upstream of with a positive effect on heparan sulfate proteoglycan biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human SLC35D2 (solute carrier family 35 member D2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 61.1), Lung (RPKM 31.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17p14

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (992153..1025476)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (987899..1019747)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (1618641..1649734, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Slc35d2 (e-PCR), detects polymorphism
- UniSTS:547091

RH132150 (e-PCR)
- UniSTS:215433

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables UDP-N-acetylgalactosamine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-N-acetylglucosamine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glucuronic acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables antiporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleotide-sugar transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in UDP-N-acetylgalactosamine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in UDP-N-acetylglucosamine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in UDP-glucuronic acid transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_positive_effect heparan sulfate proteoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in nucleotide-sugar transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in Golgi membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: nucleotide sugar transporter SLC35D2

Names: UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106098.2 → NP_001099568.2 nucleotide sugar transporter SLC35D2

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000017

UniProtKB/TrEMBL

D4A1T9

Related

ENSRNOP00000038617.5, ENSRNOT00000036212.8

Conserved Domains (1) summary

cl26744
Location:16 → 301

TPT; Triose-phosphate Transporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086035.1 Reference GRCr8

Range

992153..1025476

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006253493.5 → XP_006253555.1 nucleotide sugar transporter SLC35D2 isoform X1

UniProtKB/TrEMBL

A0A8I6AC44

Related

ENSRNOP00000091466.1, ENSRNOT00000099057.2

Conserved Domains (2) summary

pfam03151
Location:16 → 207

TPT; Triose-phosphate Transporter family

cl23754
Location:102 → 174

EamA; EamA-like transporter family
XM_039095438.2 → XP_038951366.1 nucleotide sugar transporter SLC35D2 isoform X3

Conserved Domains (1) summary

cl26744
Location:16 → 186

TPT; Triose-phosphate Transporter family
XM_039095437.2 → XP_038951365.1 nucleotide sugar transporter SLC35D2 isoform X2

Conserved Domains (1) summary

cl26744
Location:17 → 210

TPT; Triose-phosphate Transporter family