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    Olr35 olfactory receptor 35 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293140, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Olr35provided by RGD
    Official Full Name
    olfactory receptor 35provided by RGD
    Primary source
    RGD:1333428
    See related
    EnsemblRapid:ENSRNOG00000030788 AllianceGenome:RGD:1333428
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Olr35 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (163406595..163455398)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (153994678..154043281)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (164706276..164707195)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene arrestin, beta 1 Neighboring gene microRNA 326 Neighboring gene trophoblast glycoprotein-like Neighboring gene solute carrier organic anion transporter family, member 2b1 Neighboring gene olfactory receptor 36 Neighboring gene olfactory receptor family 2 subfamily AT member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Olfactory receptor OR2AT4 regulates human hair growth. Chéret J, et al. Nat Commun, 2018 Sep 18. PMID 30228264, Free PMC Article
    2. A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4. Busse D, et al. J Invest Dermatol, 2014 Nov. PMID 24999593
    3. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables olfactory receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor Olr35
    Names
    olfactory receptor gene Olr35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001000121.1 → NP_001000121.1  olfactory receptor Olr35

      See identical proteins and their annotated locations for NP_001000121.1

      Status: REVIEWED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I6K1
      Conserved Domains (1) summary
      cl21561
      Location:45 → 313
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      163406595..163455398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285103.1 → XP_063141173.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    2. XM_063285069.1 → XP_063141139.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    3. XM_063285078.1 → XP_063141148.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    4. XM_063285118.1 → XP_063141188.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    5. XM_039106070.2 → XP_038961998.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72
      Conserved Domains (1) summary
      cd13954
      Location:81 → 335
      7tmA_OR; olfactory receptors, member of the class A family of seven-transmembrane G protein-coupled receptors

    6. XM_063285114.1 → XP_063141184.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72
      Related
      ENSRNOP00000067182.3, ENSRNOT00000071384.4

    7. XM_063285098.1 → XP_063141168.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    8. XM_063285099.1 → XP_063141169.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    9. XM_063285088.1 → XP_063141158.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    10. XM_063285082.1 → XP_063141152.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    11. XM_063285083.1 → XP_063141153.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    12. XM_063285080.1 → XP_063141150.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    13. XM_063285084.1 → XP_063141154.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    14. XM_063285101.1 → XP_063141171.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    15. XM_063285076.1 → XP_063141146.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    16. XM_063285104.1 → XP_063141174.1  olfactory receptor Olr35 isoform X1

      UniProtKB/TrEMBL
      M0RC72

    17. XM_063285124.1 → XP_063141194.1  olfactory receptor Olr35 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K8Q6, Q5RJS1
      Related
      ENSRNOP00000074698.2, ENSRNOT00000051450.5
    Nucleotide Protein Strain
    Heading Accession and Version

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