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    Ldhal6b lactate dehydrogenase A-like 6B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 369018, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ldhal6bprovided by RGD
    Official Full Name
    lactate dehydrogenase A-like 6Bprovided by RGD
    Primary source
    RGD:727955
    See related
    EnsemblRapid:ENSRNOG00000062741 AllianceGenome:RGD:727955
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ldhl
    Summary
    Predicted to enable L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate metabolic process. Predicted to be located in cytoplasm. Orthologous to human LDHAL6B (lactate dehydrogenase A like 6B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See Ldhal6b in Genome Data Viewer
    Location:
    1q11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (48402997..48404420, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (45997845..45999268, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (46307853..46309276, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134484862 Neighboring gene AT-rich interaction domain 1B Neighboring gene transmembrane protein 242 Neighboring gene uncharacterized LOC120099115 Neighboring gene zinc finger DHHC-type palmitoyltransferase 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
    2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-lactate dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-lactate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lactate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lactate metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in pyruvate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pyruvate metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L-lactate dehydrogenase A-like 6B
    NP_899163.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183334.1 → NP_899163.1  L-lactate dehydrogenase A-like 6B

      See identical proteins and their annotated locations for NP_899163.1

      Status: PROVISIONAL

      Source sequence(s)
      AY342428
      UniProtKB/TrEMBL
      A0A8I6AFT6, Q7TNA8
      Related
      ENSRNOP00000093436.1, ENSRNOT00000102163.2
      Conserved Domains (2) summary
      cd05293
      Location:70 → 379
      LDH_1; A subgroup of L-lactate dehydrogenases
      TIGR01771
      Location:75 → 375
      L-LDH-NAD; L-lactate dehydrogenase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      48402997..48404420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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