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    Muc6 mucin 6, oligomeric mucus/gel-forming [ Rattus norvegicus (Norway rat) ]

    Gene ID: 282586, updated on 4-Jan-2025

    Summary

    Official Symbol
    Muc6provided by RGD
    Official Full Name
    mucin 6, oligomeric mucus/gel-formingprovided by RGD
    Primary source
    RGD:628826
    See related
    EnsemblRapid:ENSRNOG00000056817 AllianceGenome:RGD:628826
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in extracellular matrix and extracellular space. Used to study gastric ulcer. Orthologous to human MUC6 (mucin 6, oligomeric mucus/gel-forming (gene/pseudogene)). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Spleen (RPKM 9.9), Lung (RPKM 9.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Muc6 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (206155826..206194384, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (196726678..196764842, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (214608453..214630524, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 317 Neighboring gene adaptor related protein complex 2 subunit alpha 2 Neighboring gene uncharacterized LOC120097363 Neighboring gene mucin 2, oligomeric mucus/gel-forming Neighboring gene mucin 5AC, oligomeric mucus/gel-forming

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in extracellular matrix  
    is_active_in extracellular space  

    General protein information

    Preferred Names
    mucin-6
    Names
    mucin 6, gastric

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      206155826..206194384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098009.2 → XP_038953937.1  mucin-6

      UniProtKB/TrEMBL
      D4A6I9
      Related
      ENSRNOP00000071269.3, ENSRNOT00000089110.3
      Conserved Domains (5) summary
      smart00832
      Location:1061 → 1133
      C8; This domain contains 8 conserved cysteine residues
      cl17735
      Location:364 → 408
      VWC; von Willebrand factor type C domain
      pfam00094
      Location:873 → 1024
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:307 → 362
      TIL; Trypsin Inhibitor like cysteine rich domain
      cd19941
      Location:769 → 832
      TIL; trypsin inhibitor-like cysteine rich domain
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