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    Sec31b SEC31 homolog B, COPII coat complex component [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309433, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sec31bprovided by RGD
    Official Full Name
    SEC31 homolog B, COPII coat complex componentprovided by RGD
    Primary source
    RGD:1598329
    See related
    EnsemblRapid:ENSRNOG00000025781 AllianceGenome:RGD:1598329
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in COPII-coated vesicle cargo loading and endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Orthologous to human SEC31B (SEC31 homolog B, COPII coat complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 73.7), Testes (RPKM 44.1) and 5 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sec31b in Genome Data Viewer
    Location:
    1q54
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (253324081..253353779, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (243376283..243404557, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (264266279..264294687, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene stearoyl-CoA desaturase Neighboring gene Wnt family member 8B Neighboring gene NADH:ubiquinone oxidoreductase subunit B8 Neighboring gene hypoxia inducible factor 1 subunit alpha inhibitor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural molecule activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in COPII-coated vesicle cargo loading IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein transport protein Sec31B
    Names
    SEC31 homolog B, COPII coating complex component

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135713.1NP_001129185.1  protein transport protein Sec31B

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      D4ADQ9
      Conserved Domains (4) summary
      PHA03247
      Location:7981076
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:1365
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:560652
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:87334
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      253324081..253353779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264803.1XP_063120873.1  protein transport protein Sec31B isoform X9

    2. XM_063264782.1XP_063120852.1  protein transport protein Sec31B isoform X2

    3. XM_039080343.2XP_038936271.1  protein transport protein Sec31B isoform X10

      Conserved Domains (4) summary
      PHA03247
      Location:8191072
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_039080338.2XP_038936266.1  protein transport protein Sec31B isoform X7

      Conserved Domains (4) summary
      PHA03247
      Location:8191097
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    5. XM_017589280.3XP_017444769.1  protein transport protein Sec31B isoform X4

      UniProtKB/TrEMBL
      D4ADQ9
      Related
      ENSRNOP00000101165.1, ENSRNOT00000141870.1
      Conserved Domains (4) summary
      PHA03247
      Location:7981076
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:1365
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:560652
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:87334
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    6. XM_017589279.3XP_017444768.1  protein transport protein Sec31B isoform X4

      UniProtKB/TrEMBL
      D4ADQ9
      Conserved Domains (4) summary
      PHA03247
      Location:7981076
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:1365
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:560652
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:87334
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. XM_039080330.2XP_038936258.1  protein transport protein Sec31B isoform X4

      UniProtKB/TrEMBL
      D4ADQ9
      Conserved Domains (4) summary
      PHA03247
      Location:7981076
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:1365
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:560652
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:87334
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    8. XM_039080331.2XP_038936259.1  protein transport protein Sec31B isoform X5

      Conserved Domains (4) summary
      PHA03247
      Location:7861064
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:468640
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    9. XM_039080332.2XP_038936260.1  protein transport protein Sec31B isoform X6

      Related
      ENSRNOP00000038038.7, ENSRNOT00000035758.7
      Conserved Domains (4) summary
      PHA03247
      Location:8191072
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    10. XM_039080320.2XP_038936248.1  protein transport protein Sec31B isoform X3

      Conserved Domains (4) summary
      PHA03247
      Location:8041082
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:566658
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    11. XM_039080316.2XP_038936244.1  protein transport protein Sec31B isoform X1

      Conserved Domains (4) summary
      PHA03247
      Location:8191097
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    12. XM_017589278.3XP_017444767.1  protein transport protein Sec31B isoform X4

      UniProtKB/TrEMBL
      D4ADQ9
      Conserved Domains (4) summary
      PHA03247
      Location:7981076
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:1365
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:560652
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:87334
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    13. XM_017589284.3XP_017444773.2  protein transport protein Sec31B isoform X8

      Related
      ENSRNOP00000101532.1, ENSRNOT00000154301.1
      Conserved Domains (4) summary
      PHA03247
      Location:7681046
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:94131
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:530622
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:57304
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    14. XM_039080350.2XP_038936278.1  protein transport protein Sec31B isoform X13

      Conserved Domains (3) summary
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    15. XM_039080349.2XP_038936277.1  protein transport protein Sec31B isoform X12

      Conserved Domains (3) summary
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    16. XM_063264823.1XP_063120893.1  protein transport protein Sec31B isoform X14

    17. XM_039080345.2XP_038936273.1  protein transport protein Sec31B isoform X11

      Conserved Domains (3) summary
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    18. XM_039080353.2XP_038936281.1  protein transport protein Sec31B isoform X15

      Conserved Domains (3) summary
      sd00039
      Location:3486
      7WD40; WD40 repeat [structural motif]
      cl14807
      Location:581673
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      cl29593
      Location:108355
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. XR_005487399.2 RNA Sequence