Prss16 serine protease 16 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Prss16provided by RGD
Official Full Name: serine protease 16provided by RGD
Primary source: RGD:1306652
See related: EnsemblRapid:ENSRNOG00000057865 AllianceGenome:RGD:1306652
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be active in endosome and lysosome. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 880.3) See more
Orthologs: human mouse all
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Genomic context

Location:: 17p11

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (47210071..47225377)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (42514306..42521885)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (44556039..44563826)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2
Title: ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables serine-type exopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endosome	ISO Inferred from Sequence Orthology more info
located_in lysosome	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: thymus-specific serine protease

Names: protease, serine 16; protease, serine, 16 (thymus)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.