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    Ndufs6-ps1 NADH:ubiquinone oxidoreductase subunit S6, pseudogene 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29478, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufs6-ps1provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit S6, pseudogene 1provided by RGD
    Primary source
    RGD:3156
    See related
    EnsemblRapid:ENSRNOG00000018068 AllianceGenome:RGD:3156
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ndub13; Ndufs6; Ip13dis; RATIp13dis
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Biomarker of arteriosclerosis. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Orthologous to human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1030.6), Muscle (RPKM 639.6) and 8 other tissues See more
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    Genomic context

    See Ndufs6-ps1 in Genome Data Viewer
    Location:
    2q12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (28936402..28936955)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (27201706..27202241)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (26471173..26471587)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC120100552 Neighboring gene synaptic vesicle glycoprotein 2c Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134485822

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • CI-13kD-A
    • NADH dehydrogenase (ubiquinone) Fe-S protein 6
    • NADH dehydrogenase Fe-S protein 6
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
    • NADH ubiquinone oxidoreductase
    • NADH-ubiquinone oxidoreductase 13 kDa-A subunit
    • NADH:ubiquinone oxidoreductase subunit S6
    • complex I-13kD-A

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mitochondrial electron transport, NADH to ubiquinone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex I ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_228711.1 

      Range
      101..654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      28936402..28936955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_019223.2: Suppressed sequence

      Description
      NM_019223.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.