Skint1 selection and upkeep of intraepithelial T cells 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Skint1provided by RGD
Official Full Name: selection and upkeep of intraepithelial T cells 1provided by RGD
Primary source: RGD:1587579
See related: EnsemblRapid:ENSRNOG00000043194 AllianceGenome:RGD:1587579
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 28.1) See more
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Genomic context

Location:: 5q35

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (132014881..132043149)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (126786469..126814599)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (131915266..131944842)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables signaling receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in T cell receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cytokine production	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: selection and upkeep of intraepithelial T-cells protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135916.1 → NP_001129388.1 selection and upkeep of intraepithelial T-cells protein 1 isoform 1 precursor

See identical proteins and their annotated locations for NP_001129388.1

Status: PROVISIONAL

Source sequence(s)

EU650232

UniProtKB/TrEMBL

B2ZEZ3

Related

ENSRNOP00000060977.1, ENSRNOT00000064863.4

Conserved Domains (3) summary

cd05713
Location:42 → 141

Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)

smart00410
Location:36 → 140

IG_like; Immunoglobulin like

cl11960
Location:107 → 217

Ig; Immunoglobulin domain
NM_001430300.1 → NP_001417229.1 selection and upkeep of intraepithelial T-cells protein 1 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005

UniProtKB/TrEMBL

A0A8I5ZVY8