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    Nol6 nucleolar protein 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313167, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nol6provided by RGD
    Official Full Name
    nucleolar protein 6provided by RGD
    Primary source
    RGD:1308033
    See related
    EnsemblRapid:ENSRNOG00000010409 AllianceGenome:RGD:1308033
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing; ribosomal small subunit biogenesis; and tRNA export from nucleus. Predicted to be located in mitochondrion and nuclear lumen. Predicted to be part of CURI complex; UTP-C complex; and small-subunit processome. Orthologous to human NOL6 (nucleolar protein 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 48.5), Brain (RPKM 37.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nol6 in Genome Data Viewer
    Location:
    5q22
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (61055863..61083249, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (56259919..56270540, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (57444448..57473803, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene aquaporin 3 (Gill blood group) Neighboring gene uncharacterized LOC120103060 Neighboring gene ubiquitin-conjugating enzyme E2R 2 Neighboring gene small nucleolar RNA, C/D box 121B Neighboring gene ubiquitin-associated protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding  
    Process Evidence Code Pubs
    involved_in rRNA processing  
    involved_in ribosomal small subunit biogenesis  
    involved_in tRNA export from nucleus  
    Component Evidence Code Pubs
    part_of CURI complex  
    part_of UTP-C complex  
    located_in condensed nuclear chromosome  
    located_in mitochondrion  
    located_in nucleolus  
    located_in nucleoplasm  
    part_of small-subunit processome  
    part_of small-subunit processome  

    General protein information

    Preferred Names
    nucleolar protein 6
    Names
    nucleolar protein 6 (RNA-associated)
    nucleolar protein family 6 (RNA-associated)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427201.1 → NP_001414130.1  nucleolar protein 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A096MKG2, A0A0G2QC27
      Related
      ENSRNOP00000014211.7, ENSRNOT00000014211.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      61055863..61083249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287602.1 → XP_063143672.1  nucleolar protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A096MKG2, A0A0G2QC27

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