U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nxph4 neurexophilin 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 59316, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nxph4provided by RGD
    Official Full Name
    neurexophilin 4provided by RGD
    Primary source
    RGD:628723
    See related
    EnsemblRapid:ENSRNOG00000025059 AllianceGenome:RGD:628723
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Nph4
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in modulation of chemical synaptic transmission. Predicted to be located in extracellular region. Predicted to be active in GABA-ergic synapse. Orthologous to human NXPH4 (neurexophilin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 11.0), Kidney (RPKM 7.9) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nxph4 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (65253043..65261864, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (63367758..63376579, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (70833662..70842523, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene SH3 and cysteine rich domain 3 Neighboring gene NDUFA4, mitochondrial complex associated like 2 Neighboring gene serine hydroxymethyltransferase 2 Neighboring gene LDL receptor related protein 1 Neighboring gene uncharacterized LOC120093805 Neighboring gene uncharacterized LOC134479886

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in modulation of chemical synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in GABA-ergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in GABA-ergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021680.2NP_067712.2  neurexophilin-4 precursor

      See identical proteins and their annotated locations for NP_067712.2

      Status: PROVISIONAL

      Source sequence(s)
      BC081805
      UniProtKB/TrEMBL
      A0A0G2JSW7, A6HQW1
      Related
      ENSRNOP00000050310.2, ENSRNOT00000047449.5
      Conserved Domains (1) summary
      pfam06312
      Location:81303
      Neurexophilin; Neurexophilin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      65253043..65261864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)