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    Stard10 StAR-related lipid transfer domain containing 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293150, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Stard10provided by RGD
    Official Full Name
    StAR-related lipid transfer domain containing 10provided by RGD
    Primary source
    RGD:1306548
    See related
    EnsemblRapid:ENSRNOG00000019491 AllianceGenome:RGD:1306548
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable lipid binding activity. Predicted to act upstream of or within bile acid secretion and positive regulation of peroxisome proliferator activated receptor signaling pathway. Predicted to be active in several cellular components, including cytosol; intercellular canaliculus; and microvillus. Orthologous to human STARD10 (StAR related lipid transfer domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 1106.5), Kidney (RPKM 242.3) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Stard10 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (165130408..165159134)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (155722637..155748007)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (166428780..166458413)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene FCH and double SH3 domains 2 Neighboring gene ribosomal protein L7a, pseudogene 36 Neighboring gene autophagy related 16-like 2 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene uncharacterized LOC120097347 Neighboring gene phosphodiesterase 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis. Ito M, et al. Biochim Biophys Acta, 2013 Feb. PMID 23200860
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109555

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within bile acid secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of peroxisome proliferator activated receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in intercellular canaliculus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in intercellular canaliculus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in microvillus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in microvillus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    START domain-containing protein 10
    Names
    PCTP-like protein
    START domain containing 10
    StAR-related lipid transfer (START) domain containing 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013069.1 → NP_001013087.1  START domain-containing protein 10

      See identical proteins and their annotated locations for NP_001013087.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091411
      UniProtKB/TrEMBL
      A6I6U2, F7FPT5, Q5BJN1
      Conserved Domains (1) summary
      cd08871
      Location:19 → 241
      START_STARD10-like; Lipid-binding START domain of mammalian STARD10 and related proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      165130408..165159134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285179.1 → XP_063141249.1  START domain-containing protein 10 isoform X1

      UniProtKB/TrEMBL
      A0A0G2KB11, A0A8I5Y8Z4
      Related
      ENSRNOP00000075607.1, ENSRNOT00000085555.3
    Nucleotide Protein Strain
    Heading Accession and Version

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