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    Nup155 nucleoporin 155 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 117021, updated on 4-Jan-2025

    Summary

    Official Symbol
    Nup155provided by RGD
    Official Full Name
    nucleoporin 155provided by RGD
    Primary source
    RGD:621199
    See related
    EnsemblRapid:ENSRNOG00000013411 AllianceGenome:RGD:621199
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus; protein localization to nucleus; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within with a positive effect on miRNA processing and protein localization to nucleus. Predicted to act upstream of or within atrial cardiac muscle cell action potential; mRNA export from nucleus; and nuclear envelope organization. Located in nuclear envelope. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human NUP155 (nucleoporin 155). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Thymus (RPKM 139.8), Spleen (RPKM 106.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nup155 in Genome Data Viewer
    Location:
    2q16
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (58927171..58980162)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (57201310..57252918)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (57206665..57258242)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene WD repeat domain 70 Neighboring gene phospholipase D family, member 6, pseudogene 1 Neighboring gene uncharacterized LOC120100734 Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 29 Neighboring gene ciliogenesis and planar polarity effector complex subunit 1 Neighboring gene non-POU domain containing, octamer-binding, pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding PubMed 
    enables structural constituent of nuclear pore  
    enables structural constituent of nuclear pore  
    Component Evidence Code Pubs
    located_in nuclear envelope PubMed 
    located_in nuclear envelope  
    located_in nuclear membrane  
    located_in nuclear membrane  
    part_of nuclear pore  
    part_of nuclear pore inner ring  

    General protein information

    Preferred Names
    nuclear pore complex protein Nup155
    Names
    155 kDa nucleoporin
    P140
    nucleoporin 155kD
    nucleoporin Nup155

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053952.3 → NP_446404.2  nuclear pore complex protein Nup155

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      P37199
      UniProtKB/TrEMBL
      A6KGH5
      Related
      ENSRNOP00000074340.3, ENSRNOT00000082694.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      58927171..58980162
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010063579.1 RNA Sequence

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