U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Snrk SNF related kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 170837, updated on 4-Jan-2025

    Summary

    Official Symbol
    Snrkprovided by RGD
    Official Full Name
    SNF related kinaseprovided by RGD
    Primary source
    RGD:69653
    See related
    EnsemblRapid:ENSRNOG00000004050 AllianceGenome:RGD:69653
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in nucleus. Orthologous to human SNRK (SNF related kinase). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Lung (RPKM 279.9), Brain (RPKM 275.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Snrk in Genome Data Viewer
    Location:
    8q32
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130657204..130711461)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121779704..121833949)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130749806..130805225)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) Neighboring gene uncharacterized LOC134480254 Neighboring gene uncharacterized LOC134480253 Neighboring gene uncharacterized LOC120094304 Neighboring gene anoctamin 10 Neighboring gene uncharacterized LOC134480255 Neighboring gene uncharacterized LOC102552874

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Items 1 - 25 of 28
    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity  
    enables AMP-activated protein kinase activity  
    enables ATP binding PubMed 
    enables ATP binding  
    enables DNA-dependent protein kinase activity  
    enables Rho-dependent protein serine/threonine kinase activity  
    enables eukaryotic translation initiation factor 2alpha kinase activity  
    enables histone H2AS1 kinase activity  
    enables histone H2AS121 kinase activity  
    enables histone H2AT120 kinase activity  
    enables histone H2AXS139 kinase activity  
    enables histone H2BS14 kinase activity  
    enables histone H2BS36 kinase activity  
    enables histone H3S10 kinase activity  
    enables histone H3S28 kinase activity  
    enables histone H3S57 kinase activity  
    enables histone H3T11 kinase activity  
    enables histone H3T3 kinase activity  
    enables histone H3T45 kinase activity  
    enables histone H3T6 kinase activity  
    enables histone H4S1 kinase activity  
    enables magnesium ion binding PubMed 
    enables magnesium ion binding  
    enables protein serine kinase activity  
    enables protein serine/threonine kinase activity  
    enables protein serine/threonine kinase activity PubMed 
    enables protein serine/threonine kinase activity  
    enables ribosomal protein S6 kinase activity  
    Items 1 - 25 of 28
    Component Evidence Code Pubs
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    SNF-related serine/threonine-protein kinase
    Names
    SNF1-related kinase
    NP_620188.1
    XP_006244124.1
    XP_038936666.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138833.1NP_620188.1  SNF-related serine/threonine-protein kinase

      See identical proteins and their annotated locations for NP_620188.1

      Status: PROVISIONAL

      Source sequence(s)
      X89383
      UniProtKB/Swiss-Prot
      Q63553
      UniProtKB/TrEMBL
      A6I473
      Conserved Domains (2) summary
      cd14339
      Location:288335
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:12269
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130657204..130711461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244062.4XP_006244124.1  SNF-related serine/threonine-protein kinase isoform X1

      See identical proteins and their annotated locations for XP_006244124.1

      UniProtKB/Swiss-Prot
      Q63553
      UniProtKB/TrEMBL
      A6I473
      Conserved Domains (2) summary
      cd14339
      Location:288335
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:12269
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase
    2. XM_039080738.2XP_038936666.1  SNF-related serine/threonine-protein kinase isoform X1

      UniProtKB/Swiss-Prot
      Q63553
      UniProtKB/TrEMBL
      A6I473
      Related
      ENSRNOP00000071648.1, ENSRNOT00000079273.3
      Conserved Domains (2) summary
      cd14339
      Location:288335
      UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
      cd14074
      Location:12269
      STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase
    Loading
    External link. Please review our privacy policy.