U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Dnlz DNL-type zinc finger [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296587, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dnlzprovided by RGD
    Official Full Name
    DNL-type zinc fingerprovided by RGD
    Primary source
    RGD:1308635
    See related
    EnsemblRapid:ENSRNOG00000018791 AllianceGenome:RGD:1308635
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308635
    Summary
    Predicted to enable protein folding chaperone and protein-folding chaperone binding activity. Predicted to be involved in several processes, including chaperone-mediated protein complex assembly; protein import into mitochondrial matrix; and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol; mitochondrion; and nucleus. Orthologous to human DNLZ (DNL-type zinc finger). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 178.9), Adrenal (RPKM 152.6) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dnlz in Genome Data Viewer
    Location:
    3p13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (29568041..29569937, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (9169948..9171727, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (3796480..3798467, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101510 Neighboring gene coiled-coil domain containing 187 Neighboring gene G-protein signaling modulator 1 Neighboring gene caspase recruitment domain family, member 9 Neighboring gene small nuclear RNA activating complex, polypeptide 4 Neighboring gene endosome associated trafficking regulator 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Clone Names

    • MGC189536

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein folding chaperone ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNL-type zinc finger protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130990.2NP_001124462.1  DNL-type zinc finger protein

      See identical proteins and their annotated locations for NP_001124462.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6JTD6
      Conserved Domains (1) summary
      pfam05180
      Location:70135
      zf-DNL; DNL zinc finger

    RNA

    1. NR_024073.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Related
      ENSRNOT00000025386.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      29568041..29569937 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283470.1XP_063139540.1  DNL-type zinc finger protein isoform X1