Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Hs3st3b1provided by RGD
Official Full Name: heparan sulfate-glucosamine 3-sulfotransferase 3B1provided by RGD
Primary source: RGD:1307326
See related: EnsemblRapid:ENSRNOG00000003384 AllianceGenome:RGD:1307326
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hs3st3b
Summary: Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to be involved in branching involved in ureteric bud morphogenesis; glycosaminoglycan biosynthetic process; and heparan sulfate proteoglycan biosynthetic process. Predicted to act upstream of or within protein sulfation. Predicted to be located in plasma membrane. Orthologous to human HS3ST3B1 (heparan sulfate-glucosamine 3-sulfotransferase 3B1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 69.7), Spleen (RPKM 32.8) and 6 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 10q23

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (49060693..49093185, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (48561473..48593970, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (50369097..50402584, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

UniSTS:493827 (e-PCR)
- UniSTS:493827

Hs3st3b1 (e-PCR), detects polymorphism
- UniSTS:532547

Hs3st3b1 (e-PCR), detects polymorphism
- UniSTS:532608

RH136988 (e-PCR)
- UniSTS:219077

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	IBA Inferred from Biological aspect of Ancestor more info
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in branching involved in ureteric bud morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in glycosaminoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in heparan sulfate proteoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein sulfation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: heparan sulfate glucosamine 3-O-sulfotransferase 3B1

Names: heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1

NP_001178575.1

EC 2.8.2.30

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191646.1 → NP_001178575.1 heparan sulfate glucosamine 3-O-sulfotransferase 3B1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

D3ZTA9

Related

ENSRNOP00000004546.3, ENSRNOT00000004546.8

Conserved Domains (1) summary

pfam00685
Location:137 → 374

Sulfotransfer_1; Sulfotransferase domain