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    Lztfl1 leucine zipper transcription factor-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316102, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lztfl1provided by RGD
    Official Full Name
    leucine zipper transcription factor-like 1provided by RGD
    Primary source
    RGD:1306628
    See related
    EnsemblRapid:ENSRNOG00000006244 AllianceGenome:RGD:1306628
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of protein localization to ciliary membrane. Predicted to act upstream of or within flagellated sperm motility and spermatogenesis. Predicted to be located in cilium; cytosol; and manchette. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 17. Orthologous to human LZTFL1 (leucine zipper transcription factor like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 200.1), Testes (RPKM 197.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lztfl1 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (132222339..132237757, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (123344085..123360245, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (132774393..132790922, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene SAC1 like phosphatidylinositide phosphatase Neighboring gene solute carrier family 6 member 20b Neighboring gene solute carrier family 6 member 20a Neighboring gene ribosomal biogenesis factor, pseudogene 1 Neighboring gene C-C motif chemokine receptor 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC108960

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in manchette ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    leucine zipper transcription factor-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024266.1NP_001019437.1  leucine zipper transcription factor-like protein 1

      See identical proteins and their annotated locations for NP_001019437.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092585
      UniProtKB/Swiss-Prot
      Q562C6
      UniProtKB/TrEMBL
      A6I4C3
      Related
      ENSRNOP00000071325.2, ENSRNOT00000091431.3
      Conserved Domains (1) summary
      pfam15294
      Location:20294
      Leu_zip; Leucine zipper

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      132222339..132237757 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244191.3XP_006244253.1  leucine zipper transcription factor-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006244253.1

      UniProtKB/Swiss-Prot
      Q562C6
      UniProtKB/TrEMBL
      A6I4C3
      Conserved Domains (1) summary
      pfam15294
      Location:20294
      Leu_zip; Leucine zipper

    RNA

    1. XR_005487858.2 RNA Sequence