U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Plekhs1 pleckstrin homology domain containing S1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499377, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Plekhs1provided by RGD
    Official Full Name
    pleckstrin homology domain containing S1provided by RGD
    Primary source
    RGD:1559884
    See related
    EnsemblRapid:ENSRNOG00000072172 AllianceGenome:RGD:1559884
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559884
    Summary
    Biomarker of glucose intolerance. Orthologous to human PLEKHS1 (pleckstrin homology domain containing S1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 41.9), Thymus (RPKM 15.9) and 5 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Plekhs1 in Genome Data Viewer
    Location:
    1q55
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (265500524..265533352)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (255495634..255525353)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (277261493..277294194)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene hyaluronan binding protein 2 Neighboring gene nebulin-related anchoring protein Neighboring gene caspase 7 Neighboring gene uncharacterized LOC103691381 Neighboring gene ribosomal protein L19, pseudogene 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Plekhs1 and Prdx3 are candidate genes responsible for mild hyperglycemia associated with obesity in a new animal model of F344-fa-nidd6 rat. Kotoh J, et al. J Vet Med Sci, 2016 Dec 1. PMID 27523322, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    pleckstrin homology domain-containing family S member 1
    Names
    pleckstrin homology domain containing, family S member 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134613.1 → NP_001128085.1  pleckstrin homology domain-containing family S member 1

      See identical proteins and their annotated locations for NP_001128085.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473986
      UniProtKB/TrEMBL
      A6JI23
      Conserved Domains (2) summary
      pfam00169
      Location:21 → 128
      PH; PH domain
      cl17171
      Location:20 → 127
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      265500524..265533352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271784.1 → XP_063127854.1  pleckstrin homology domain-containing family S member 1 isoform X1

      Related
      ENSRNOP00000103699.1, ENSRNOT00000148722.1

    2. XM_063271789.1 → XP_063127859.1  pleckstrin homology domain-containing family S member 1 isoform X5

    3. XM_063271786.1 → XP_063127856.1  pleckstrin homology domain-containing family S member 1 isoform X2

    4. XM_063271790.1 → XP_063127860.1  pleckstrin homology domain-containing family S member 1 isoform X6

    5. XM_063271787.1 → XP_063127857.1  pleckstrin homology domain-containing family S member 1 isoform X3

    6. XM_063271788.1 → XP_063127858.1  pleckstrin homology domain-containing family S member 1 isoform X4

    7. XM_063271791.1 → XP_063127861.1  pleckstrin homology domain-containing family S member 1 isoform X7

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.