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    Fsd2 fibronectin type III and SPRY domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308779, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fsd2provided by RGD
    Official Full Name
    fibronectin type III and SPRY domain containing 2provided by RGD
    Primary source
    RGD:1305167
    See related
    EnsemblRapid:ENSRNOG00000019278 AllianceGenome:RGD:1305167
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305167
    Summary
    Orthologous to human FSD2 (fibronectin type III and SPRY domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 313.9) and Heart (RPKM 228.3) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fsd2 in Genome Data Viewer
    Location:
    1q31
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (144898499..144931753, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (135484002..135522517, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (143364867..143398123, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102555928 Neighboring gene cDNA sequence BC048679-like Neighboring gene small Cajal body-specific RNA 15 Neighboring gene small nucleolar RNA SNORA76 Neighboring gene WASP homolog associated with actin, golgi membranes and microtubules Neighboring gene homer scaffold protein 2 Neighboring gene RNA, U6 small nuclear 946

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    fibronectin type III and SPRY domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191627.1 → NP_001178556.1  fibronectin type III and SPRY domain-containing protein 2

      See identical proteins and their annotated locations for NP_001178556.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6JCG8, D4ADN6
      Conserved Domains (4) summary
      smart00060
      Location:368 → 453
      FN3; Fibronectin type 3 domain
      PRK12704
      Location:203 → 307
      PRK12704; phosphodiesterase; Provisional
      cd00063
      Location:465 → 557
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl02614
      Location:561 → 737
      SPRY; SPRY domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      144898499..144931753 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229440.5 → XP_006229502.1  fibronectin type III and SPRY domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006229502.1

      UniProtKB/TrEMBL
      A6JCG8, D4ADN6
      Related
      ENSRNOP00000026089.6, ENSRNOT00000026089.9
      Conserved Domains (4) summary
      smart00060
      Location:368 → 453
      FN3; Fibronectin type 3 domain
      PRK12704
      Location:203 → 307
      PRK12704; phosphodiesterase; Provisional
      cd00063
      Location:465 → 557
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl02614
      Location:561 → 737
      SPRY; SPRY domain

    2. XM_039113049.2 → XP_038968977.1  fibronectin type III and SPRY domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A6JCG8, D4ADN6
      Conserved Domains (4) summary
      smart00060
      Location:368 → 453
      FN3; Fibronectin type 3 domain
      PRK12704
      Location:203 → 307
      PRK12704; phosphodiesterase; Provisional
      cd00063
      Location:465 → 557
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl02614
      Location:561 → 737
      SPRY; SPRY domain

    3. XM_063262717.1 → XP_063118787.1  fibronectin type III and SPRY domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A6JCG8, D4ADN6
    Nucleotide Protein Strain
    Heading Accession and Version

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