Bora bora, aurora kinase A activator [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Boraprovided by RGD
Official Full Name: bora, aurora kinase A activatorprovided by RGD
Primary source: RGD:1309522
See related: EnsemblRapid:ENSRNOG00000024798 AllianceGenome:RGD:1309522
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1309522
Summary: Predicted to enable protein kinase binding activity. Predicted to be involved in regulation of mitotic nuclear division; regulation of mitotic spindle organization; and regulation of protein localization. Predicted to be located in meiotic spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human BORA (BORA aurora kinase A activator). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 94.3), Spleen (RPKM 65.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15q21

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (82205467..82243499)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (75797624..75835599)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (83442217..83463737)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in regulation of mitotic nuclear division	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic nuclear division	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic nuclear division	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of mitotic spindle organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic spindle organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic spindle organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of protein localization	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in meiotic spindle	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein aurora borealis

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013997.1 → NP_001014019.1 protein aurora borealis

See identical proteins and their annotated locations for NP_001014019.1

Status: PROVISIONAL

Source sequence(s)

BC088204

UniProtKB/Swiss-Prot

Q5M864

UniProtKB/TrEMBL

A6HU54

Related

ENSRNOP00000035098.3, ENSRNOT00000039344.6

Conserved Domains (1) summary

pfam15280
Location:8 → 207

BORA_N; Protein aurora borealis N-terminus

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086033.1 Reference GRCr8

Range

82205467..82243499

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039093376.2 → XP_038949304.1 protein aurora borealis isoform X2

UniProtKB/TrEMBL

A6HU54

Related

ENSRNOP00000083042.2, ENSRNOT00000102440.2

Conserved Domains (1) summary

pfam15280
Location:8 → 207

BORA_N; Protein aurora borealis N-terminus
XM_039093375.2 → XP_038949303.1 protein aurora borealis isoform X1

UniProtKB/Swiss-Prot

Q5M864

UniProtKB/TrEMBL

A6HU54

Conserved Domains (1) summary

pfam15280
Location:8 → 207

BORA_N; Protein aurora borealis N-terminus
XM_039093377.2 → XP_038949305.1 protein aurora borealis isoform X3