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    Susd3 sushi domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306810, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Susd3provided by RGD
    Official Full Name
    sushi domain containing 3provided by RGD
    Primary source
    RGD:1310933
    See related
    EnsemblRapid:ENSRNOG00000016525 AllianceGenome:RGD:1310933
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in plasma membrane. Orthologous to human SUSD3 (sushi domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 116.8), Testes (RPKM 49.0) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Susd3 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (15607259..15623322)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (15400845..15417851)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (15814132..15830328)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S12 like 8 Neighboring gene BICD cargo adaptor 2 Neighboring gene FYVE, RhoGEF and PH domain containing 3 Neighboring gene uncharacterized LOC134482823 Neighboring gene caspase recruitment domain family, member 19 Neighboring gene ninjurin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells. Moy I, et al. Oncogene, 2015 Jan 15. PMID 24413080, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    sushi domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107341.2 → NP_001100811.1  sushi domain-containing protein 3

      See identical proteins and their annotated locations for NP_001100811.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6J6X1, D3Z8I2
      Related
      ENSRNOP00000031097.4, ENSRNOT00000032997.6
      Conserved Domains (1) summary
      cd00033
      Location:33 → 93
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      15607259..15623322
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253709.5 → XP_006253771.1  sushi domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZSB4, A6J6X3
      Related
      ENSRNOP00000081141.1, ENSRNOT00000105376.2
      Conserved Domains (1) summary
      cd00033
      Location:8 → 68
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    Nucleotide Protein Strain
    Heading Accession and Version

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