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    Mlec malectin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304543, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mlecprovided by RGD
    Official Full Name
    malectinprovided by RGD
    Primary source
    RGD:1307736
    See related
    EnsemblRapid:ENSRNOG00000064601 AllianceGenome:RGD:1307736
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307736
    Summary
    Predicted to enable carbohydrate binding activity and enzyme binding activity. Predicted to be involved in protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum. Predicted to be part of oligosaccharyltransferase complex. Predicted to be active in membrane. Orthologous to human MLEC (malectin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 365.8), Adrenal (RPKM 267.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mlec in Genome Data Viewer
    Location:
    12q16
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (47118918..47133598)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (41458234..41468710)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (47219071..47233769)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene calcium binding protein 1 Neighboring gene uncharacterized LOC134481303 Neighboring gene uncharacterized LOC102548245 Neighboring gene unc-119 lipid binding chaperone B Neighboring gene acyl-CoA dehydrogenase short chain

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC108831

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of oligosaccharyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013983.1NP_001014005.1  malectin precursor

      See identical proteins and their annotated locations for NP_001014005.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089839
      UniProtKB/Swiss-Prot
      Q5FVQ4
      UniProtKB/TrEMBL
      A6J1W6
      Related
      ENSRNOP00000035497.4, ENSRNOT00000038395.6
      Conserved Domains (1) summary
      pfam11721
      Location:47207
      Malectin; Di-glucose binding within endoplasmic reticulum

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      47118918..47133598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271352.1XP_063127422.1  malectin isoform X1