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    Snx30 sorting nexin family member 30 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298033, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snx30provided by RGD
    Official Full Name
    sorting nexin family member 30provided by RGD
    Primary source
    RGD:1311367
    See related
    EnsemblRapid:ENSRNOG00000017132 AllianceGenome:RGD:1311367
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311367
    Summary
    Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including endocytic recycling; macroautophagy; and positive regulation of autophagosome assembly. Predicted to be located in early endosome membrane. Predicted to be active in early endosome and phagophore assembly site. Orthologous to human SNX30 (sorting nexin family member 30). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 132.8), Kidney (RPKM 121.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snx30 in Genome Data Viewer
    Location:
    5q24
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (79478804..79608118)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (74683902..74813013)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (77052445..77161964)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene INTS3 and NABP interacting protein Neighboring gene transfer RNA serine (anticodon AGA) 22 Neighboring gene transfer RNA alanine (anticodon AGC) 81 Neighboring gene solute carrier family 46, member 2 Neighboring gene alpha-2u globulin PGCL4 Neighboring gene zinc finger protein 37, pseudogene 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in piecemeal microautophagy of the nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in reticulophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in early endosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in early endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-30

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106651.1 → NP_001100121.1  sorting nexin-30

      See identical proteins and their annotated locations for NP_001100121.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474039
      UniProtKB/TrEMBL
      A6KDX6, D4A060
      Related
      ENSRNOP00000107590.1, ENSRNOT00000161925.1
      Conserved Domains (2) summary
      cd06860
      Location:91 → 206
      PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
      cd07667
      Location:190 → 429
      BAR_SNX30; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 30

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      79478804..79608118
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287322.1 → XP_063143392.1  sorting nexin-30 isoform X1

      UniProtKB/TrEMBL
      D4A060

    2. XM_063287324.1 → XP_063143394.1  sorting nexin-30 isoform X3

      UniProtKB/TrEMBL
      D4A060
      Related
      ENSRNOP00000056176.5, ENSRNOT00000059419.6

    3. XM_063287323.1 → XP_063143393.1  sorting nexin-30 isoform X2

      UniProtKB/TrEMBL
      D4A060
      Related
      ENSRNOP00000109497.1, ENSRNOT00000156988.1

    4. XM_039109447.2 → XP_038965375.1  sorting nexin-30 isoform X4

      UniProtKB/TrEMBL
      D4A060
      Related
      ENSRNOP00000102520.1, ENSRNOT00000157957.1
      Conserved Domains (2) summary
      cd06860
      Location:91 → 206
      PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
      cl12013
      Location:190 → 422
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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