Naa11 N(alpha)-acetyltransferase 11, NatA catalytic subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Naa11provided by RGD
Official Full Name: N(alpha)-acetyltransferase 11, NatA catalytic subunitprovided by RGD
Primary source: RGD:1564723
See related: EnsemblRapid:ENSRNOG00000002031 AllianceGenome:RGD:1564723
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ard1b
Summary: Predicted to enable peptide-glutamate-alpha-N-acetyltransferase activity and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation. Predicted to be located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Predicted to be part of NatA complex. Orthologous to human NAA11 (N-alpha-acetyltransferase 11, NatA catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 44.7), Heart (RPKM 9.2) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14p22

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (12487652..12497688)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (12183651..12193687)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (13827615..13838642)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables peptide alpha-N-acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables peptide-alanine-alpha-N-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables peptide-glutamate-alpha-N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptide-serine-alpha-N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in N-terminal protein amino acid acetylation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
part_of NatA complex	IBA Inferred from Biological aspect of Ancestor more info
part_of NatA complex	ISO Inferred from Sequence Orthology more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 11

Names: Ard2; N-terminal acetyltransferase complex ARD1 subunit homolog B; alpha-N-acetyltransferase 1B; natA catalytic subunit Naa11

NP_001019913.1

EC 2.3.1.255

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024742.1 → NP_001019913.1 N-alpha-acetyltransferase 11

See identical proteins and their annotated locations for NP_001019913.1

Status: PROVISIONAL

Source sequence(s)

BC097350

UniProtKB/Swiss-Prot

Q4V8K3

Related

ENSRNOP00000002776.4, ENSRNOT00000002776.7

Conserved Domains (1) summary

COG0456
Location:1 → 153

RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]