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    Pramel preferentially expressed antigen in melanoma-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 503464, updated on 9-Dec-2024

    Summary

    Symbol
    Pramelprovided by RGD
    Full Name
    preferentially expressed antigen in melanoma-likeprovided by RGD
    Primary source
    RGD:1561307
    See related
    EnsemblRapid:ENSRNOG00000068726 AllianceGenome:RGD:1561307
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561307
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 27.2) See more
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    Genomic context

    See Pramel in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (102744421..102780220)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (98451199..98486998)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (105937118..105939860)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene preferentially expressed antigen in melanoma-like 3 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene nuclear RNA export factor 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC503464
    Names
    leucine-rich repeat-containing protein PRAME-like
    melanoma antigen preferentially expressed in tumors-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419568.1NP_001406497.1  uncharacterized protein LOC503464

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6IVI7, D4AAM5, D4ABN6
      Related
      ENSRNOP00000081416.1, ENSRNOT00000113007.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      102744421..102780220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280266.1XP_063136336.1  uncharacterized protein LOC503464 isoform X1

      UniProtKB/TrEMBL
      A6IVI7, D4AAM5, D4ABN6

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001109368.1: Suppressed sequence

      Description
      NM_001109368.1: This RefSeq was removed because currently there is insufficient support for the transcript.