U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cyp4f37 cytochrome P450, family 4, subfamily f, polypeptide 37 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691312, updated on 9-Dec-2024

    Summary

    Symbol
    Cyp4f37provided by RGD
    Full Name
    cytochrome P450, family 4, subfamily f, polypeptide 37provided by RGD
    Primary source
    RGD:1585102
    See related
    EnsemblRapid:ENSRNOG00000048450 AllianceGenome:RGD:1585102
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be involved in small molecule metabolic process. Predicted to be located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 30.4), Thymus (RPKM 24.0) and 9 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cyp4f37 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (12223085..12262381)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (11572573..11595063)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (14588868..14615428)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 17 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 5 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene lactate dehydrogenase A, pseudogene 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in small molecule metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 4F5; cytochrome P450, family 4, subfamily f, polypeptide 37
    Names
    cytochrome P450 4F5-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      12223085..12262381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039080045.2XP_038935973.1  cytochrome P450 4F5 isoform X1

      UniProtKB/TrEMBL
      F7F0Y6, Q9EQ70
      Related
      ENSRNOP00000056957.5, ENSRNOT00000060210.6
      Conserved Domains (1) summary
      cd20679
      Location:74517
      CYP4F; cytochrome P450 family 4, subfamily F
    2. XM_039080046.2XP_038935974.1  cytochrome P450 4F5 isoform X2

      UniProtKB/TrEMBL
      A0A1W2Q6H4
      Conserved Domains (1) summary
      cd20679
      Location:3405
      CYP4F; cytochrome P450 family 4, subfamily F

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001271352.1: Suppressed sequence

      Description
      NM_001271352.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.