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    Ly49i4 Ly49 inhibitory receptor 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 494204, updated on 9-Dec-2024

    Summary

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    Symbol
    Ly49i4provided by RGD
    Full Name
    Ly49 inhibitory receptor 4provided by RGD
    Primary source
    RGD:1549758
    See related
    EnsemblRapid:ENSRNOG00000051600 AllianceGenome:RGD:1549758
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 22.6), Lung (RPKM 6.7) and 3 other tissues See more
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    Genomic context

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    See Ly49i4 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (165852010..165873606, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (164166784..164188380, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (164515105..164537019, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene Ly49 stimulatory receptor 6 Neighboring gene Ly49 stimulatory receptor 4 Neighboring gene killer cell lectin-like receptor, subfamily A, member 4, pseudogene 2 Neighboring gene killer cell lectin-like receptor, subfamily A, member 5, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity. Kveberg L, et al. Immunogenetics, 2006 Nov. PMID 17028855
    2. The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex. Nylenna O, et al. Eur J Immunol, 2005 Jan. PMID 15593300

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ly49 inhibitory receptor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009495.3 → NP_001009495.1  Ly49 inhibitory receptor 4

      See identical proteins and their annotated locations for NP_001009495.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      Q5MPW9
      Related
      ENSRNOP00000073809.1, ENSRNOT00000087796.3
      Conserved Domains (2) summary
      cd03593
      Location:145 → 260
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:40 → 158
      Ly49; Ly49-like protein, N-terminal region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      165852010..165873606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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